At trezor.io/start, begin the setup of your Trezor hardware wallet. Connect your device and follow instructions to install Trezor Bridge software. You'll create a new wallet or recover an existing one using your recovery seed. Secure your wallet with a PIN and backup your recovery seed. The site offers tips on protecting your recovery seed and using your Trezor securely. Follow all steps meticulously to ensure the safety of your cryptocurrencies.